No effect of polymorphisms in prothrombotic genes on the risk of myocardial infarction in young adults without cardiovascular risk factors.

نویسندگان

  • C H Martini
  • C J M Doggen
  • C Cavallini
  • F R Rosendaal
  • P M Mannucci
چکیده

Bretaudiere J. Factor VII gene intronic mutation in a lethal Factor VII deficiency: effects on splice-site selection. Blood 2003; 102: 561–3. 10 Rosen E, Chan JCY, Idusogie E, Clotman F, Vlasuk G, Luther T, Jalbert LR, Albrecht S, Zhong L, Lissens A, Schoonjans L, Collen D, Costellino FJ, Carmeliet P. Mice lacking Factor VII develop normally but suffer fatal perinatal bleeding. Nature 1997; 390: 290. 11 Peyvandi F, Mannucci PM, Jenkins PV, Lee A, Cappola R, Perry DJ. Homozygous 2 pb deletion in the human factor VII gene: a non lethal mutation that is associated with a complete absence of circulating factor VII. Thromb Haemost 2000; 84: 635–7. 12 Marechetti G, Patracchini P, Gemmati D, De Rosa V, Pinotti M, Rodorigo G, Casonato A, Girolami A, Bernardi F. Detection of two missense mutations and characterization of a repeat polymorphism in the factor VII gene. Hum Genet 1992; 89: 497–502. 13 Bernardi F, Liney DL, Patracchini P, Gemmati D, Legnani C, Arcieri P, Pinotti M, Redaelli R, Ballerini G, Pemberton S, Wacey AI, Mariani G, Tuddenham EGD, Marchetti G. Molecular defects in CRM+ factor VII deficiencies: modelling of missenses mutations in the catalytic domain of factor VII. Br J Haematol 1994; 86: 610–8.

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عنوان ژورنال:
  • Journal of thrombosis and haemostasis : JTH

دوره 3 1  شماره 

صفحات  -

تاریخ انتشار 2005